External Antiparasitic Pestigon Cats

Composition:
A pipette of 0.5 ml contains:
Active ingredient: Fipronil 50 mg
Excipients: Butylhydroxyanisole (E320) 0.1 mg, Butylated hydroxytoluene (E321) 0.05 mg, Povidone K12, Polysorbate 80. Butyl alcohol, diethylene glycol monoethyl ether

Pharmaceutical form:
Solution transparent, colorless to pale yellow, for anointing dorsalpuntual (Spot-on)

Indications:
In cats, for the treatment of flea infestation (Ctenocephalides felis). The drug shows an insecticidal effect immediately and persistence against new infestations with adult fleas for up to 5 weeks.

Contraindications:
In the absence of available data, the drug should not be used on kittens under 8 weeks old and / or weighing less than 1 kg.
Do not use on sick (systemic diseases, fever ...) or convalescent.
Do not use in rabbits, as adverse reactions may occur to the active substance or any of the excipients.
No animals usaren conhipersensibilidad to lasustancia aalgún active or excipient.

Precautions to be taken by the person administering the medication the animals:
This medication may cause irritation to mucous membranes and eyes. Therefore, avoid contact of the drug with mouth and eyes.
In case of accidental contact with eyes, immediately flush eyes with water. If the eyes irritaciónde persist, consult a doctor immediately and show the package leaflet.
Avoid the substance comes into contact with the fingers. If it occurs, wash hands with soap and water. Do not smoke, drink or eat during application.
People with known hypersensitivity to fipronil or some of its excipientesdeben avoid contact with the veterinary medicinal product.
Treated animals should not be handled until the application site is dry and should not allow children to play with treated animals until the injection point is dry. It is therefore recommended that animals are not treated during the day, but at sunset, and should not allow recently treated animals to sleep with owners, especially children.

Adverse reactions:
If the animal licks, one can observe a hypersalivation period mainly due to the nature of the excipient.
Among the extremely rare suspected adverse reactions have been observed transient skin reactions at the point of application (desquamation, alopecia local pruritus, erythema) and pruritus or general alopecia after use. In exceptional cases, it has been observed hypersalivation, reversible neurological signs (hyperaesthesia, depression, nervous signs) or vomiting.

Use during pregnancy, lactation and commissioning:
Laboratory studies using fipronil have not shown any teratogenic and fetotoxic.
No studies have been conducted in pregnant or lactating using this medicamentoveterinario therefore use during pregnancy and lactation should only be carried out after the evaluaciónbeneficio / risk assessment by elveterinario responsible.

Dosage & Administration:
Pipette 0.5 ml per cat (aproximadamente7 ,5-15 mg / kg)
Hold upright. Give a tap to make sure that all the liquid content is within the main body of the pipette. Peel off the top by the dashed line and separate the hair between the shoulder blades until the skin is visible. Place the tip of the pipette on the skin and squeeze the pipette to empty its contents, preferably at two points, one at the base of the skull and the second at 2-3 cm lower.
It is important to ensure that the product is applied in an area where the animal can not remove licking, and also to ensure that if multiple animals otrosdespués lick each treatment.
Care should be taken to avoid excessive wetting of the hair with the drug since this will produce a hair sticky appearance at the point of treatment. However, in case this occurs, disappear within 24 hours after application.

Pharmacodynamic Properties
Fipronil is an insecticide / acaricide belonging to the family of the phenylpyrazole. It acts by inhibiting the GABA complex, joining the chloride channel and thus blocking the pre-transfer and post-synaptic chloride ions across the membrane. This results in uncontrolled activity of the central nervous system and therefore the death of insects and mites.
Fipronil acts as an insecticide against fleas (Ctenocephalidesspp) in elgato.
The pulgasque lleganmueren a 24 hour plazode elanimal posarseen.
The drug is effective against flea infestation for about 5 weeks depending on the level of challenge.

Presentation:
Pipette 0.5 ml, molded by a surface composed of three layers: a layer of polypropylene / COC / polypropylene foil lacquer-free solvent, and a layer of polyethylene / EVOH / polyethylene. The pipettes are sealed in envelopes composed of four layers of LDPE / nylon / aluminum foil / polyester layer.